In 1562 Pope Pius IV commissioned Daniele da Volterra to replace the old ceiling with a deeply coffered wooden ceiling that still covers the nave. The ceiling was designed by da Volterra and Pirro Ligorio and was created by the French cabinet maker Flaminio Boulanger.
There are three papal coats-of-arms in the ceiling, occupying the three main coffers: Pope Pius IV (Medici, 1559-1565) in the center, those of St. Pius V (1566-1572) at the far end and Pius VI (1775-1799) at the entrance. The side coffers feature the Instruments of the Passion in the center, and Eucharistic symbols at each end. The gilding is fabulously rich, with backgrounds in red and blue with a little green.
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