The chapel is dedicated to St. Joseph. The Marquis Scipione Lancellotti acquired the patronage of the chapel in 1629 and the remains of St. Luige Gonzaga were brought here. In 1709 the chapel was granted to Cardinal Giuseppe Sacripanti. The task of restoration was given to Nicola Michetti, and various artists were called upon to tend to the pictorial decoration. The altar is decorated with two columns cased in verde antico.