Set in an urban scene with a chessboard-like pavement, painted using geometrical perspective that has its vanishing point in an edifice with central plan, taken from Perugino's Delivery of the Keys. Pinturicchio, however, departed from that model by using two buildings of different heights at the sides. On the left is a loggiato, supported by piers decorated with fanciful gilded candelabra. On the right is a cubic building connected through a double loggia to the landscape and the bright sky in the background. The surrounding characters are used to portray a series of miracles attributed to Bernardino during his life.