This chapel had been rebuilt a number of times before the 18th century. In 1725 Pope Benedict XIII, a Dominican, commissiond the total rebuilding of it, directed by Filippo Raguzzini. The Pope (d. 1730) is buried in the majestic funeral monument on the right. On the left, the statue of the Madonna with three children - the Divine Child, St John the Baptist and St John the Evangelist, was made by Francesco Grassia in 1670.