The first chapel to the right, commissioned by the Marchesa Vittoria della Tolfa, wife of Camillo Orsini and niece of Pope Paul IV. The architect was probably Ottavio Mascarino as it was constructed at the same time as the façade. The chapel must have been completed by 1588, the year on the inscription in the dado to the left, an inscription which was placed there by Theseo Aldovrandi, and the year on the memorial stone of Vittoria Tolfa, owner of the chapel.